What is Tezspire​?

Tezspire (tezepelumab-ekko) is a prescription biologic medication approved by the FDA as an add-on maintenance treatment for severe asthma in adults and children aged 12 years and older. It is intended for patients whose asthma remains uncontrolled despite standard therapies. Unlike some other asthma treatments, Tezspire is effective across various asthma phenotypes, regardless of biomarker levels such as eosinophil counts or allergic status.

Tezspire targets and inhibits thymic stromal lymphopoietin (TSLP), a cytokine involved in initiating airway inflammation. By blocking TSLP, Tezspire helps prevent the inflammatory cascade that leads to asthma exacerbations, thereby improving breathing and reducing the frequency of severe asthma attacks.