What is Alzheimer’s Disease?
Alzheimer’s disease was discovered in 1906 by Dr. Alois Alzheimer when he examined the brain of a woman who appeared to have died from a mental illness that caused memories issues and erratic behavior. Upon examining this patient’s brain, he found abnormal lumps throughout the brain’s tissues and tangled bundles of fiber. These hallmarks of Alzheimer’s disease are now referred to as amyloid plaques and tau tangles, which are believed to inhibit the connections between neurons in the brain.
As the ability for nerves to connect in the brain worsens, memory problems and other cognitive deficits begin to present in those afflicted with disease, making it the 7th leading cause of death in the United States.
Common Symptoms of Alzheimer’s Disease Include:
- Disruptive memory loss
- Inability or difficulty completing everyday tasks
- Struggling to solve problems or plan for the future
- Confusion
- Mood swings
- Repetition of questions or statements
- Difficulty with writing or speaking
- Getting lost easily
How is Alzheimer’s Disease Treated?
There is currently no cure of Alzheimer’s disease. However, Leqembi & Kinsula, both biologics, is a FDA approved disease modifying medication meant to treat the early stages of Alzheimer’s disease. However, there are other medications that are used to lessen symptoms, but ultimately will not slow the progression of the disease.
Some of these medications and therapies used to temporarily improve the symptoms and challenging behaviors of Alzherimer’s disease include acetylcholinesterase (AChE) inhibitors, memantine, antipsychotics, antidepressants, and cognitive stimulation therapy.
